This condition occurs when the periosteum, the connective tissue surrounding bone, becomes inflamed. If you ignore it, this issue can lead to a stress fracture. It occurs due to repeated trauma to your connected muscle tissue by the shinbone (known as the tibia). This injury commonly affects runners and causes pain from knee to ankle. Most people know medial tibial stress syndrome as shin splints. The stress can transfer to nearby bone, leading to small fractures that aren’t visible on regular X-rays. Eventually, the muscles are overloaded or fatigued to the point where they can’t absorb the shock or stress of repeated impacts and instead begin braking. Stress fractures develop slowly due to repetitive trauma. It can also be accompanied by numbness or weakness. Pain in the case of compartment syndrome is typically exercise-induced and you will experience relief with rest. It can affect any lower leg compartments, with the anterior compartment most likely to be affected. Compartment SyndromeĬompartment syndrome or chronic exertional compartment syndrome occurs if you repeatedly engage in exertional or loading activities. Some of the most common causes of pain from knee to ankle are related to injuries of muscles, joints, and bones. Lower Leg Pain Caused by Bones, Joints, and Muscle Problems Pain in your lower legs may be due to issues with nerves, blood clots, or a number of other potential problems. Even though your legs are affected the most by your daily activities, you shouldn’t be in pain. In most cases, those who have pain from their knee to ankle have lower leg pain. It can appear as pain from knees to ankles, in the foot, in the knee, behind the knee, in the ankle, down the back of your leg, etc.

Emg test of ankle and knee pain